Resource Type

Journal Article 420

Year

2024 1

2023 27

2022 34

2021 41

2020 26

2019 41

2018 26

2017 28

2016 18

2015 21

2014 19

2013 25

2012 11

2011 20

2010 11

2009 23

2008 9

2007 12

2006 2

2005 2

open ︾

Keywords

fuel cell 13

immunotherapy 8

solar cell 6

hematopoietic stem cell transplantation 5

hydrogen energy 5

stem cell 5

cell proliferation 4

control 4

lung cancer 4

microbial fuel cell 4

solid oxide fuel cell 4

Alzheimer’s disease 3

COVID-19 3

chemotherapy 3

hepatocellular carcinoma 3

prognosis 3

solid oxide fuel cell (SOFC) 3

Apoptosis 2

Biomaterial 2

open ︾

Search scope:

排序： Display mode:

Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1,   Pages 9-19 doi: 10.1007/s11705-013-1306-9

Abstract: research, an innovative silica-based, mucoadhesive oral insulin formulation with encapsulated-insulin/cellpenetrating peptide (CPP) to overcome both enzyme and mucosal barriers is discussed, and the preliminaryIt was also confirmed that low molecular weight protamine (LMWP) behaves like a CPP peptide, with a celldevelopment of a generic platform for oral delivery of many other bioactive compounds, especially for peptide

Keywords： insulin     cell penetrating peptide     mucoadhesive composites     oral delivery    

HTML PDF Collect

Cationic and amphipathic cell-penetrating peptides (CPPs): Their structures and

Jennica L. Zaro,Wei-Chiang Shen

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 4,   Pages 407-427 doi: 10.1007/s11705-015-1538-y

Abstract: Over the past few decades, cell penetrating peptides (CPPs) have become an important class of drug carriersCPPs represent a very diverse set of short peptide sequences (10?

Keywords： cell penetrating peptides     amphipathic peptides     drug delivery    

HTML PDF Collect

Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating

Xinghong Duo, Lingchuang Bai, Jun Wang, Jintang Guo, Xiangkui Ren, Shihai Xia, Wencheng Zhang, Abraham Domb, Yakai Feng

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 5,   Pages 889-901 doi: 10.1007/s11705-020-1919-8

Abstract: Herein, the multitargeting REDV-G-TAT-G-NLS peptide was conjugated to amphiphilic cationic copolymerOwing to ECs-targeting ability, cell-penetrating ability and nuclear targeting capacity of REDV-G-TAT-G-NLSpeptide, the multitargeting polycationic gene carrier with low cytotoxicity and high transfection efficiency

Keywords： gene carriers     multitargeting function     ECs     transfection efficiency    

HTML PDF Collect

Erratum to: Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating and nuclear accumulation

Xinghong Duo, Lingchuang Bai, Jun Wang, Jintang Guo, Xiangkui Ren, Shihai Xia, Wencheng Zhang, Abraham Domb, Yakai Feng

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 1,   Pages 220-220 doi: 10.1007/s11705-020-1995-9

HTML PDF Collect

Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 433-444 doi: 10.1007/s11705-014-1454-6

Abstract: Previous studies have found that three peptide inhibitors (i.e., KLVFF, VVIA, and LPFFD) can inhibitHowever, atomic details of binding modes and binding affinities between these peptide inhibitors andmolecular mechanics Poisson Boltzmann surface area (MM/PBSA) analysis, we examined the effect of three peptideMM/PBSA analysis further revealed that different peptide inhibitors have different modes of interactionprovides structure-based binding information for further modification and optimization of these three peptide

Keywords： Alzheimer’s disease     amyloid β-protein     peptide inhibitors     protein-protein interaction     molecular    

HTML PDF Collect

Cystine oligomers successfully attached to peptide cysteine-rich fibrils

Christian Bortolini,Mingdong Dong

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 1,   Pages 99-102 doi: 10.1007/s11705-016-1554-6

Abstract: Amyloid peptides are renowned to be related to neurodegenerative diseases, however, a fruitful avenue is to employ them as high-performance nanomaterials. These materials benefit from the intrinsic outstanding mechanical robustness of the amyloid backbone made of -strands. In this work, we exploited amyloid-like fibrils as functional material to attach pristine L-cysteine aggregates (cystine oligomers) and gold nanoparticles, without the need of templating compounds. This work will open new avenues on functional materials design and their realisation.

Keywords： cysteine     peptide fibrils     gold nanoparticles     amyloids     oligomers     nanomaterials    

HTML PDF Collect

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 368-373 doi: 10.1007/s11684-015-0403-1

Abstract:

Glucagon-like peptide-2 (GLP-2) has potent anti-inflammatory effects and protects against experimental

Keywords： ischemia/reperfusion     liver     glucagon-like peptide-2     alanine aminotransferase    

HTML PDF Collect

Earth-penetrating Weapons and Their Experiments Upon Gas Gun

Lin Junde

Strategic Study of CAE 2003, Volume 5, Issue 11,   Pages 25-33

Abstract:

The history and the actualities of developing earth-penetrating weapon are described.The technical difficulties for developing low-yield earth-penetrating nuclear weapons have not been primaryThe experimental results indicate that there is a favorable analogical relation among earth-penetratingA method for calculating profiles on acceleration, velocity and displacement of penetrating projectileupon penetrating depth data is introduced.

Keywords： test of weapon     earth penetrating     gas gun     impact     experimental technique    

HTML PDF Collect

The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease

Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 437-442 doi: 10.1007/s11684-009-0074-x

Abstract: Natriuretic peptide precursor A (NPPA) is synthesized, stored, and released by atrial myocytes.

Keywords： natriuretic peptide precursor A     coronary heart disease     gene polymorphism     allelic discrimination     polymorphism    

HTML PDF Collect

Significance and strategies in developing delivery systems for bio-macromolecular drugs

Huining HE, Qiuling LIANG, Meong Cheol SHIN, Kyuri LEE, Junbo GONG, Junxiao YE, Quan LIU, Jingkang WANG, Victor YANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4,   Pages 496-507 doi: 10.1007/s11705-013-1362-1

Abstract: the drug on tumor cells as opposed to normal tissues, and (2) the lack of ability to cross the tumor cell

Keywords： delivery systems     bio-macromolecular drugs     cell penetrating peptides    

HTML PDF Collect

Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation

Haishan Qi,Yihang Gao,Lin Zhang,Zhongxin Cui,Xiaojie Sui,Jianfan Ma,Jing Yang,Zhiquan Shu,Lei Zhang,

Engineering doi: 10.1016/j.eng.2023.01.015

Abstract: In particular, a designed antifreeze peptide named AVD exhibits ideal ice recrystallization inhibitionanalysis and molecular dynamics (MD) simulations indicated that the Thr6 and Asn8 residues of the AVD peptideFurthermore, to demonstrate the cryoprotection potential of AVD, the peptide was successfully employedfor the cryopreservation of various cells, which demonstrated significant post-freezing cell recoveryThis work opens up a new avenue for designing antifreeze materials and provides peptide-based functional

Keywords： Antifreeze peptides     Evolution analysis     Ice recrystallization inhibition     Molecular dynamics simulation     Cryopreservation     Synthetic biology    

HTML PDF Collect

Multi-Peptide Adsorption on Uncharged Solid Surfaces: A Coarse-Grained Simulation Study Research

Ruosang Qiu, Jie Xiao, Xiao Dong Chen

Engineering 2020, Volume 6, Issue 2,   Pages 185-194 doi: 10.1016/j.eng.2018.12.012

Abstract: It was observed that around half (46.6%) of the 12-Ala peptide chains could form aggregates. 30.0% ofThe change in the solid-liquid interface due to peptide deposition has a potential influence on the furtheradsorption of single peptide chains and aggregates in the bulk water.Overall, the findings from this work help to reveal the mechanism of multi-peptide adsorption, and consequentially

Keywords： Peptide chains     Aggregates     Adsorption     Coarse-grained simulation    

HTML PDF Collect

The damage effect of earth penetrating weapons and key scientific problems of deep buried protective

Fan Pengxian,Qian Qihu,Wang Mingyang

Strategic Study of CAE 2013, Volume 15, Issue 5,   Pages 47-58

Abstract: The earth penetrating weapons (nuclear and non-nuclear) developing by countries with military power haveOn the summary of the developing earth penetrating weapons, the damage effects of earth penetrating weaponsare reviewed, with emphasis on penetrating effect, crater effect and explosion ground shock effect.

Keywords： earth penetrating weapons     damage effect     deep buried     protective engineering    

HTML PDF Collect

Reverse-Time Migration from Rugged Topography to Image Ground-Penetrating Radar Data in Complex Environments Article

John H. Bradford,Janna Privette,David Wilkins,Richard Ford

Engineering 2018, Volume 4, Issue 5,   Pages 661-666 doi: 10.1016/j.eng.2018.09.004

Abstract: text-align:justify">In ground-penetrating

Keywords： Ground-penetrating radar     Reverse-time migration     Sand dune     Amplitude analysis    

HTML PDF Collect

Experimental investigation of lavge-loading projectile penetrating

Zhao Shengwei,Gu Renhong,Chu Zhe,Li Ming

Strategic Study of CAE 2009, Volume 11, Issue 8,   Pages 44-47

Abstract: Axial acceleration was evaluated by SAPLL. penetration process of projectile on penetrating concretePenetration depth and structure intensity of projectile were examined by a series of experiments on penetratingA conclusion is obtained, projectile isn't destroyed during penetrating concrete target,and reinforced

Keywords： thin-walls projectile     concrete     penetration depth    

HTML PDF Collect

Title Author Date Type Operation

Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

Journal Article

Cationic and amphipathic cell-penetrating peptides (CPPs): Their structures and

Jennica L. Zaro,Wei-Chiang Shen

Journal Article

Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating

Xinghong Duo, Lingchuang Bai, Jun Wang, Jintang Guo, Xiangkui Ren, Shihai Xia, Wencheng Zhang, Abraham Domb, Yakai Feng

Journal Article

Erratum to: Multifunctional peptide conjugated amphiphilic cationic copolymer for enhancing ECs targeting, penetrating and nuclear accumulation

Xinghong Duo, Lingchuang Bai, Jun Wang, Jintang Guo, Xiangkui Ren, Shihai Xia, Wencheng Zhang, Abraham Domb, Yakai Feng

Journal Article

Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-

Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG

Journal Article

Cystine oligomers successfully attached to peptide cysteine-rich fibrils

Christian Bortolini,Mingdong Dong

Journal Article

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Journal Article

Earth-penetrating Weapons and Their Experiments Upon Gas Gun

Lin Junde

Journal Article

The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease

Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,

Journal Article

Significance and strategies in developing delivery systems for bio-macromolecular drugs

Huining HE, Qiuling LIANG, Meong Cheol SHIN, Kyuri LEE, Junbo GONG, Junxiao YE, Quan LIU, Jingkang WANG, Victor YANG

Journal Article

Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation

Haishan Qi,Yihang Gao,Lin Zhang,Zhongxin Cui,Xiaojie Sui,Jianfan Ma,Jing Yang,Zhiquan Shu,Lei Zhang,

Journal Article

Multi-Peptide Adsorption on Uncharged Solid Surfaces: A Coarse-Grained Simulation Study

Ruosang Qiu, Jie Xiao, Xiao Dong Chen

Journal Article

The damage effect of earth penetrating weapons and key scientific problems of deep buried protective

Fan Pengxian,Qian Qihu,Wang Mingyang

Journal Article

Reverse-Time Migration from Rugged Topography to Image Ground-Penetrating Radar Data in Complex Environments

John H. Bradford,Janna Privette,David Wilkins,Richard Ford

Journal Article

Experimental investigation of lavge-loading projectile penetrating

Zhao Shengwei,Gu Renhong,Chu Zhe,Li Ming

Journal Article